New Therapeutic Targets for Mood Disorders

New therapeutic targets for mood disorders.

Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in putative novel treatments for mood disorders. These include: (1) glycogen synthase kinase-3 (GSK-3) and protein kinase C (PKC), (2) the purinergic ...

New therapeutic options for anxiety and mood disorders.

New targets for new therapeutic approaches

Because of its resistance profiles, Pseudomonas aeruginosa remains probably one of the challenging bacteria responsible for ventilator-associated pneumonia in the ICU. Nevertheless, a much better understanding of its mechanism of virulence, such as the type 3 secretion system that can also impact on resistance, gives some opportunities for management improvement. The most promising approach is ...

New psychotherapies for mood and anxiety disorders.

OBJECTIVE To discuss psychotherapies for depression and anxiety that have emerged in recent years and to evaluate their current level of empirical support. METHOD An electronic and a manual literature search of psychotherapies for mood and anxiety disorders were conducted. RESULTS Five new therapies for mood disorders and 3 interventions for posttraumatic stress disorder with co-occurring s...

New Therapeutic Targets